Association of retinal microvascular abnormalities with all-cause and specific-cause mortality among U.S. adults.

ABSTRACT:

Background

Retinal microvascular abnormalities (RMA) reflect cumulative microvascular damage from systemic diseases and aging. However, little is known about the association between RMA and long-term survival outcomes. This study aimed to examine the relationships between RMA and the risk of all-cause and specific-cause mortality among U.S. adults.

Methods

Individuals aged ≥ 40 years were included from the U.S. National Health and Nutrition Examination Survey, 2005-2008. RMA and its subtypes, including retinopathy, arteriovenous nicking (AVN), focal arteriolar narrowing (FAN) and Hollenhorst plaque (HP), were manually graded from retinal photographs. Associations between RMA and the risk of all-cause and cause-specific mortality were examined with Cox regression analysis.

SUBMITTER: Chen X 

PROVIDER: S-EPMC11667902 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature