Functional characterization of the second feedback loop in the circadian clock of the Antarctic krill Euphausia superba.

ABSTRACT:

Background

The Antarctic krill Euphausia superba is a keystone species in the Southern Ocean ecosystem. This crustacean has an ancestral clock whose main components have been identified and characterized in the past few years. However, the second feedback loop, modulating clock gene expression through two transcription factors, VRI and PDP1, has yet to be described. The presence of this second regulatory mechanism is suggested by the identification of its negative component, vrille, at the transcriptional level.

Results

Here, we describe the second feedback loop of krill by identifying the positive component, pdp1, and functionally characterizing both pdp1 and vrille. Starting from the online transcriptome database KrillDB², we identified and cloned three putative

SUBMITTER: Stefanelli C 

PROVIDER: S-EPMC11668059 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature