Molecular characterization and antimicrobial susceptibility for 62 isolates of Bordetella pertussis from children.

ABSTRACT:

Background

Pertussis is a highly contagious respiratory disease caused by Bordetella pertussis (BP). Despite global control of pertussis cases through the Expanded Programme on Immunization (EPI), there has been a significant increase in the incidence of pertussis in recent years, characterized by a "resurgence" in developed countries with high immunization rates as well as a comparable reemergence in certain areas of China. We aim to explore the genotypes and antimicrobial susceptibility of circulating BP from children in Hebei.

Study design

Children diagnosed with BP infection from 2019 to 2020 in Hebei, China were enrolled. We performed antimicrobial susceptibility testing (AST), whole-genome sequencing (WGS) analysis, single nucleotide polymorphism (SNP) detection

SUBMITTER: He B 

PROVIDER: S-EPMC11668733 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature