Multi-omics analysis reveals interactions between host and microbes in Bama miniature pigs during weaning.

ABSTRACT:

Introduction

There are complex interactions between host and gut microbes during weaning, many of the mechanisms are not yet fully understood. Previous research mainly focuses on commercial pigs, whereas limited information has been known about the host and gut microbe interactions in miniature pigs.

Methods

To address the issue in Bama miniature piglets that were weaned 30 days after birth, we collected samples on days 25 and 36 for metabolomics, transcriptomics, and microgenomics analysis.

Results and discussion

The average daily weight gain of piglets during weaning was only 58.1% and 40.6% of that during 0-25 days and 36-60 days. Metabolomic results identified 61 significantly different metabolites (SDMs), of which, the most significantly increased and decreased S

SUBMITTER: Ma W 

PROVIDER: S-EPMC11668797 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature