Antiplatelet therapy is not associated with increased risk of complications after lumbar puncture.

ABSTRACT:

Background

Lumbar puncture (LP) is a critical diagnostic procedure in the evaluation of neurological diseases. Although considered safe, complications such as post-dural puncture headache (PDPH), back pain, subdural hematoma or venous sinus thrombosis may still occur. Whether the use of antiplatelet therapy (APT) increases the risk of complications after LP, remains unclear.

Methods

This retrospective observational study included 783 patients who underwent diagnostic LP. We employed multivariate logistic regression models with complications as the dependent variable, and APT as the independent variable, adjusting for potential confounders.

Results

Among 783 patients included (54.0% female, median age 48 years [IQR 33-64], median BMI 24.7 kg/m² [IQR 21.8-28.

SUBMITTER: Stichaller L 

PROVIDER: S-EPMC11668846 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature