Shifts in naturalistic behaviors induced by early social isolation stress are associated with adult binge-like eating in female rats.

ABSTRACT: Binge eating (BE) is a highly pervasive maladaptive coping strategy in response to severe early life stress such as emotional and social neglect. BE is described as repeated episodes of uncontrolled eating and is tightly linked with comorbid mental health concerns. Despite social stressors occurring at a young age, the onset of BE typically does not occur until adulthood providing an interval for potential therapeutic intervention. Currently, our knowledge of longitudinal noninvasive digital biomarkers predictive of BE needs further development. Monitoring longitudinal impacts of adolescent social isolation stress on naturalistic behaviors in rats will enable the identification of noninvasive digital markers of disease progression to predict adult eating strategies. Recognizing adolescent

SUBMITTER: Simon TB 

PROVIDER: S-EPMC11669510 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature