Exploring the Laws of Developmental Direction Using a Documented Skeletal Collection.

ABSTRACT:

Objectives

Many human growth studies note a trend of differential variation in limb segment lengths, where distal elements show greater variability than their proximal counterparts. This has been attributed to their developmental sequence, where bones further from the head develop later and are more impacted by fluctuating growth conditions. We aimed to explore limb dimensions within this framework, known as the laws of developmental direction, in children (0.09-11.75 years) from a documented skeletal collection of low socioeconomic status.

Materials and methods

Z-scores were generated for diaphyseal length measurements of six limb bones. Differences between mean z-score values of the limbs, as well as of the proximal and distal segments of each limb, were assessed using pai

SUBMITTER: Nelson JS 

PROVIDER: S-EPMC11669766 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature