Safety of ACEI/ARB use in the early (<3 months) post kidney transplant period: a systematic review and meta-analysis.

ABSTRACT:

Background

Data about the safety of ACEI/ARB use in early (<3 months) posttransplant period are restricted and remain controversial.

Methods

This systematic review and meta-analysis included searches of PubMed, Embase and CENTRAL from inception to 31 November 2023, for studies to compare the safety (transplant outcomes and postoperative complications) of ACEI/ARB with non-ACEI/ARB (other antihypertensive medications) initiation in early post kidney transplant period.

Results

Of 1,247 citations identified, 13 eligible studies involving 1919 patients were enrolled for analyses. In short- or long-term observations, there were no differences on pooled serum creatinine between ACEI/ARB and non-ACEI/ARB groups whether initiated within 1 or 1-3 months posttransplant, however

SUBMITTER: Fu D 

PROVIDER: S-EPMC11670068 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature