Photosynthetic demands on translational machinery drive retention of redundant tRNA metabolism in plant organelles.

ABSTRACT: Eukaryotic nuclear genomes often encode distinct sets of translation machinery for function in the cytosol vs. organelles (mitochondria and plastids). This raises questions about why multiple translation systems are maintained even though they are capable of comparable functions and whether they evolve differently depending on the compartment where they operate. These questions are particularly interesting in plants because translation machinery, including aminoacyl-transfer RNA (tRNA) synthetases (aaRS), is often dual-targeted to the plastids and mitochondria. These organelles have different functions, with much higher rates of translation in plastids to supply the abundant, rapid-turnover proteins required for photosynthesis. Previous studies have indicated that plant organellar aaRS evo

SUBMITTER: DeTar RA 

PROVIDER: S-EPMC11670086 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature