Longitudinal trend in post-discharge estimated glomerular filtration rate in intensive care survivors.

ABSTRACT:

Background

Acute kidney injury (AKI) within the intensive care unit (ICU) is common but evidence is limited on longer-term renal outcomes. We aimed to model the trend of kidney function in ICU survivors using estimated glomerular filtration rate (eGFR), comparing those with and without AKI, and investigate potential risk factors associated with eGFR decline.

Methods

This observational cohort study included all patients aged 16 or older admitted to two general adult ICUs in Scotland between 1st July 2015 and 30th June 2018 who survived to 30 days following hospital discharge. Baseline serum creatinine and subsequent values were used to identify patients with AKI and calculate eGFR following hospital discharge. Mixed effects modelling was used to control for repeated measures

SUBMITTER: Glendell RM 

PROVIDER: S-EPMC11670225 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature