An interkinetic envelope surrounds chromosomes between meiosis I and II in C. elegans oocytes.

ABSTRACT: At the end of cell division, the nuclear envelope reassembles around the decondensing chromosomes. Female meiosis culminates in two consecutive cell divisions of the oocyte, meiosis I and II, which are separated by a brief transition phase known as interkinesis. Due to the absence of chromosome decondensation and the suppression of genome replication during interkinesis, it has been widely assumed that the nuclear envelope does not reassemble between meiosis I and II. By analyzing interkinesis in C. elegans oocytes, we instead show that an atypical structure made of two lipid bilayers, which we termed the interkinetic envelope, surrounds the surface of the segregating chromosomes. The interkinetic envelope shares common features with the nuclear envelope but also exhibits specific characte

SUBMITTER: El Mossadeq L 

PROVIDER: S-EPMC11670776 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature