Associations between neonicotinoids and inflammation in US adults using hematological indices: NHANES 2015-2016.

ABSTRACT:

Background

Toxicological studies suggest neonicotinoids increase oxidative stress and inflammation, but few epidemiological studies have explored these effects.

Methods

National Health and Nutrition Examination Survey (NHANES) 2015-2016 data were used to estimate associations between neonicotinoid exposure and inflammatory markers, including the C-reactive protein-to-lymphocyte count ratio (CLR), monocyte-to-high-density lipoprotein ratio (MHR), monocyte-to-lymphocyte ratio (MLR), neutrophil-to-lymphocyte ratio (NLR), derived NLR (dNLR), lymphocyte-to-monocyte ratio, platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII) using linear and multinomial logistic regression models. Sex was evaluated as a potential modifier.

Results

Detection of an

SUBMITTER: Godbole AM 

PROVIDER: S-EPMC11671084 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature