Association of tooth location, occlusal support and chewing ability with cognitive decline and incident dementia.

ABSTRACT:

Aim

Emerging evidence suggests association of tooth loss with impaired cognition. However, the differential effects of anterior versus posterior tooth loss, occlusal support loss and chewing ability are not considered comprehensively.

Materials and methods

We conducted cross-sectional (N = 4036) and longitudinal analyses (N = 2787) on data from Health 2000 and 2011 Surveys for associations of posterior occlusal support loss, anterior versus posterior tooth loss, and chewing ability with baseline cognition and 11-year cognitive decline. Additionally, 15-year incident dementia risk was investigated (N = 4073).

Results

After considering relevant confounders and potential reverse causality bias, posterior occlusal support loss significantly increased dementia risk across

SUBMITTER: Asher S 

PROVIDER: S-EPMC11671170 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature