Acquisition Efficiency and Technical Repeatability of Dual-Frequency 3D Vector MR Elastography of the Liver.

ABSTRACT:

Background

MR elastography (MRE) at 60 Hz is widely used for staging liver fibrosis. MRE with lower frequencies may provide inflammation biomarkers.

Purpose

To establish a practical simultaneous dual-frequency liver MRE protocol at both 30 Hz and 60 Hz during a single examination and validate the occurrence of second harmonic waves at 30 Hz.

Study type

Retrospective.

Subjects

One hundred six patients (48 females, age: 50.0 ± 13.4 years) were divided as follows: Cohort One (15 patients with chronic liver disease [CLD] and 25 healthy volunteers) with simultaneous dual-frequency MRE. Cohort Two (66 patients with CLD) with second harmonic MRE.

Field strength/sequence

3-T, single- or dual-frequency MRE at 30 Hz and 60 Hz.

Assessment

Liver stiffness (LS

SUBMITTER: Qiu C 

PROVIDER: S-EPMC11671616 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature