Validating Simple Modifications to the Rome IV Criteria for the Diagnosis of Irritable Bowel Syndrome in Secondary Care.

ABSTRACT:

Background

The Rome IV criteria for irritable bowel syndrome (IBS) may be too restrictive for clinical practice and research.

Aims

To validate the Rome IV criteria and study the diagnostic performance of simple modifications to them.

Methods

We collected symptom data from consecutive adults with suspected IBS seen in a single clinic. We used a reference standard to confirm IBS (presence of lower abdominal pain associated with altered stool form or frequency; no evidence of organic gastrointestinal disease after limited investigation). We applied Rome IV criteria, but also two modifications. First, we re-incorporated abdominal discomfort but kept symptom frequency required for both abdominal pain and discomfort to at least 1 day per week. Second, we included only abdom

SUBMITTER: Goodoory VC 

PROVIDER: S-EPMC11671724 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature