Febrile neutropenia prophylaxis, G-CSF physician preferences: discrete-choice experiment.

ABSTRACT:

Objectives

Febrile neutropenia (FN) commonly occurs during cancer chemotherapy. Prophylaxis with granulocyte colony-stimulating factors (G-CSFs) is known to reduce the severity and incidence of FN and infections in patients with cancer. Despite the proven efficacy, G-CSFs are not always prescribed as recommended. We performed a discrete-choice experiment (DCE) to determine what factors drive the physician preference for FN prophylaxis in patients with cancer undergoing chemotherapy.

Methods

Attributes for the DCE were selected based on literature search and on expert focus group discussions and comprised pain at the injection site, presence of bone pain, associated fever/influenza syndrome, efficacy of prophylaxis, biosimilar availability, number of injections per chemothera

SUBMITTER: Scotte F 

PROVIDER: S-EPMC11672075 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature