Selective Segregation of Thermo-Responsive Microgels via Microfluidic Technology.

ABSTRACT: Separation of equally sized particles distinguished solely by material properties remains still a very challenging task. Here a simple separation of differently charged, thermo-responsive polymeric particles (for example microgels) but equal in size, via the combination of pressure-driven microfluidic flow and precise temperature control is proposed. The separation principle relies on forcing thermo-responsive microgels to undergo the volume phase transition during heating and therefore changing its size and correspondingly the change in drift along a pressure driven shear flow. Different thermo-responsive particle types such as different grades of ionizable groups inside the polymer matrix have different temperature regions of volume phase transition temperature (VPTT). This enables selec

SUBMITTER: Sharma A 

PROVIDER: S-EPMC11672189 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature