Leukocyte telomere length decreased the risk of mortality in patients with alcohol-associated liver disease.

ABSTRACT:

Background

It is necessary to find latent indicators to predict the survival of alcohol-associated liver disease (ALD) patients. Leukocyte telomere length (LTL) was regarded as an indicator of prognosis in several diseases. However, the relationships between LTL and survival as well as cause-specific mortality in ALD patients were still unknown.

Objective

This study aimed at exploring the underlying link between LTL and the risk of mortality in patients with ALD.

Methods

The LTL and survival data were gathered from the National Health and Nutrition Examination Survey (NHANES) 1999-2002. The connection between LTL and mortality was assessed by Cox regression models and stratified analyses. The non-linear relationship was explored by restricted cubic spline (RCS) analys

SUBMITTER: Yi J 

PROVIDER: S-EPMC11672197 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature