Spatiotemporal Encapsulation of Tandem Enzymes in Hierarchical Metal-Organic Frameworks for Cofactor-Dependent Photoenzymatic CO₂ Conversion.

ABSTRACT: The photo-enzyme coupling system (PECS) holds immense potential in "green" biomanufacturing, encompassing the realms of pharmaceuticals, fuels, and carbon sequestration. Nevertheless, the intricate nature of enzymes' structures significantly impedes the seamless integration of multiple enzymes in a precise, tandem fashion, with exact control over their distribution, posing a formidable challenge. Herein, it has devised a mesoporous csq-type metal organic framework (Zr-MOF) from meso-tetrakis-(4-((phenyl)ethynyl)benzoate)porphyrin (Por-PTP) and Zr₆(μ₃-O)₄(μ₃-OH)₄(OH)₄(H₂O)₄) nodes (Zr₆ clusters), featuring intricate hierarchical hexagonal (5.8 nm) and triangular (2.9 nm) channels, enabling the

SUBMITTER: Li Y 

PROVIDER: S-EPMC11672261 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature