Increased Levels of Anti-<i>Anisakis</i> Antibodies During Hospital Admission in Septic Patients.

ABSTRACT:

Background/objectives

In a previous study, we described elevated anti-Anisakis IgG levels in septic patients in relation to disease severity. In this study, our objective was to analyze the evolution of anti-Anisakis immunoglobulins in septic patients during hospital admission and their association with αβ and γδ T cell subsets.

Methods

We recruited 80 subjects: 40 patients with sepsis and 40 controls. αβ and γδ T cells were analyzed using flow cytometry. Apoptosis was also assessed, and anti-Anisakis antibodies were measured by ELISA in the sera of patients with sepsis and controls.

Results

In the second analysis (7-10 after sepsis evolution), an increase in all specific antibody isotypes was identified in individuals with septic shock, except Ig

SUBMITTER: Andreu-Ballester JC 

PROVIDER: S-EPMC11672462 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature