High-Speed Sequential DNA Computing Using a Solid-State DNA Origami Register.

ABSTRACT: DNA computing leverages molecular reactions to achieve diverse information processing functions. Recently developed DNA origami registers, which could be integrated with DNA computing circuits, allow signal transmission between these circuits, enabling DNA circuits to perform complex tasks in a sequential manner, thereby enhancing the programming space and compatibility with various biomolecules of DNA computing. However, these registers support only single-write operations, and the signal transfer involves cumbersome and time-consuming register movements, limiting the speed of sequential computing. Here, we designed a solid-state DNA origami register that compresses output data from a 3D solution to a 2D surface, establishing a rewritable register suitable for solid-state storage. We deve

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC11672539 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature