Broccoli Byproduct Extracts Attenuate the Expression of UVB-Induced Proinflammatory Cytokines in HaCaT Keratinocytes.

ABSTRACT: Broccoli byproducts are an important source of bioactive compounds, which provide important benefits for human skin due mainly to their antioxidant and anti-inflammatory properties. The primary target of UVB radiation is the basal layer of cells in the epidermis, with keratinocytes being the most abundant cell population in this layer. Given the wide range of side effects caused by exposure to UVB radiation, reducing the amount of UV light that penetrates the skin and strengthening the protective mechanisms of the skin are interesting strategies for the prevention of skin disorders. This work aims to evaluate the protective mechanisms triggered by broccoli by-products extract (BBE) on HaCaT keratinocytes exposed to UVB radiation as well as the study of the regenerative effect of these extr

SUBMITTER: Borja-Martinez M 

PROVIDER: S-EPMC11673147 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature