Onset and predictors of first-line antiretroviral therapy treatment failure among children in Ethiopia: a systematic review and meta-analysis.

ABSTRACT:

Introduction

The emergence of First-line Antiretroviral Therapy (ART) regimens fails; it necessitates the use of more costly and less tolerable second-line medications. Therefore, it is crucial to identify and address factors that increase the likelihood of first-line ART regimen failure in children. Although numerous primary studies have examined the incidence of first-line ART failure among HIV-infected children in Ethiopia, national-level data on the onset and predictors remain inconsistent. Hence, this study was conducted to fill the gaps in determining the onset of first-line ART failure and its predictors among HIV-infected children in Ethiopia.

Methods

Articles related to our topic of interest were searched using a systematic approach in national and international ele

SUBMITTER: Birhanu MY 

PROVIDER: S-EPMC11673881 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature