Feasibility and safety of ultra-low volume ventilation (≤ 3 ml/kg) combined with extra corporeal carbon dioxide removal (ECCO₂R) in acute respiratory failure patients.

ABSTRACT:

Background

Ultra-protective ventilation is the combination of low airway pressures and tidal volume (Vt) combined with extra corporeal carbon dioxide removal (ECCO₂R). A recent large study showed no benefit of ultra-protective ventilation compared to standard ventilation in ARDS (Acute Respiratory Distress Syndrome) patients. However, the reduction in Vt failed to achieve the objective of less than or equal to 3 ml/kg predicted body weight (PBW). The main objective of our study was to assess the feasibility of the ultra-low volume ventilation (Vt ≤ 3 ml/kg PBW) facilitated by ECCO₂R in acute respiratory failure patients.

Methods

Retrospective analysis of a prospective cohort of patients with either high or low blood flow veno-venous ECCO₂R de

SUBMITTER: Monet C 

PROVIDER: S-EPMC11674201 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature