Fertility-Related Concerns in Long-Term Survivors of Childhood Cancer: A Canadian Cohort Study.

ABSTRACT: Survivors of childhood cancer face reduced fertility, which can be a significant cause for concern. Our study aimed to assess the prevalence of fertility-related concerns and identify associated factors. Self-report data were collected with the Long-Term Survivor Questionnaire at the Alberta Children's Hospital's Long-Term Survivor Clinic (LTSC) between January 2021 and September 2023. Eligible participants were diagnosed before the age of 21 years, ≥2 years off therapy, and ≥13 years old. We analyzed fertility-related concerns cross-sectionally for the whole sample and longitudinally for a subsample of participants that completed three questionnaires. We included N = 311 survivors (49.2% female; mean age = 22.7 years, range = 13.9-42.1; mean time since diagnosis = 14.5 years, range

SUBMITTER: Holmer P 

PROVIDER: S-EPMC11674506 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature