Complete genomic profiles of 1496 Taiwanese reveal curated medical insights.

ABSTRACT:

Introduction

The population of Taiwan has a long history of ethno-cultural evolution. The Taiwanese population was isolated from other large populations such as the European, Han Chinese, and Japanese population. The Taiwan Biobank (TWB) project has built a nationwide database, particularly for personal whole-genome sequence (WGS) to facilitate basic and clinical collaboration nationally and internationally, making it one of the most valuable public datasets of the East Asian population.

Objectives

This study provides comprehensive medical genomic findings from TWB WGS data, for better characterization of disease susceptibility and the choice of ideal treatment regimens in Taiwanese population.

Methods

We reanalyzed 1496 WGS using a PrecisionFDA Truth challenge winner

SUBMITTER: Hsu JS 

PROVIDER: S-EPMC11675050 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature