CXCL10, SCGN, and H2BC5 as Potential Key Genes Regulated by HCV Infection.

ABSTRACT: Introduction: Hepatitis C infections are the main causes of fatal clinical conditions such as cirrhosis and HCC development, and biomarkers are needed to predict the development of these complications. Therefore, it is important to first determine which genes are deregulated in HCV-cells compared to healthy individuals. In our study, we aimed to identify the genes that are commonly upregulated or downregulated in HCV-infected cells using two different databases. Material and Method: In this study, differentially expressed genes (DEGs) that were commonly upregulated or downregulated were identified using publicly available databases GSE66842 and GSE84587. Afterwards, the interactions of DEG products with each other and other proteins were examined using the STRING database. En

SUBMITTER: Yıldırım C 

PROVIDER: S-EPMC11675613 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature