Dynamic Double-Networked Hydrogels by Hybridizing PVA and Herbal Polysaccharides: Improved Mechanical Properties and Selective Antibacterial Activity.

ABSTRACT: Chinese herbal medicine has offered an enormous source for developing novel bio-soft materials. In this research, the natural polysaccharide isolated from the Chinese herbal medicine Dendrobium was employed as the secondary building block to fabricate a "hybrid" hydrogel with synthetic poly (vinyl alcohol) (PVA) polymers. Thanks to the presence of mannose units that contain cis-diol motifs on the chain of the Dendrobium polysaccharides, efficient crosslinking with the borax is allowed and reversible covalent borate ester bonds are formed. Eventually, highly dynamic and double-networked hydrogels were successfully prepared by the integration of Dendrobium polysaccharides and PVA. Interestingly, the introduction of polysaccharides has given rise to more robust and dynami

SUBMITTER: Liu W 

PROVIDER: S-EPMC11675697 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature