Risk Factors Related to Resting Metabolic Rate-Related DNAJC6 Gene Variation in Children with Overweight/Obesity: 3-Year Panel Study.

ABSTRACT: This study investigated how the DNACJ6 gene variation related to RMR alteration affects risk factors of obese environments in children with obesity aged 8-9.

Methods

Over a three-year follow-up period, 63.3% of original students participated. Changes in the variables (anthropometrics, blood biochemistry, and dietary intakes) were analyzed and compared between those without obesity (non-OB) and with obesity (OB) classified at the study endpoint.

Result

The average MAF of nine SNPs (D-1 to D-IX) was defined as 18.1%. The OB group showed greater increases in RMR, BMI, WC, and SBP, while the non-OB group had significantly greater increases in HDL and intakes of nutrients (e.g., total calories, vitamins B2, C, folate, A, retinol, iron, and zinc). Increased RMR

SUBMITTER: Shin J 

PROVIDER: S-EPMC11676649 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature