ClustAll: An R package for patient stratification in complex diseases.

ABSTRACT: In the era of precision medicine, it is necessary to understand heterogeneity among patients with complex diseases to improve personalized prevention and management strategies. Here, we introduce ClustAll, a Bioconductor package designed for unsupervised patient stratification using clinical data. ClustAll is based on the previously validated methodology ClustAll, a clustering framework that effectively handles intricacies in clinical data, including mixed data types, missing values, and collinearity. Additionally, ClustAll stands out in its ability to identify multiple patient stratifications within the same population while ensuring their robustness. The updated implementation of ClustAll features S4 classes, parallel computing for enhanced computational efficiency, and user-friendly too

SUBMITTER: Ortega-Legarreta A 

PROVIDER: S-EPMC11676920 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature