Sequential Bone Repair in Rabbit Sinus Lifts Using Bio-Oss and Hyaluronic Acid-Polynucleotide Gel (Regenfast).

ABSTRACT:

Background

A comprehensive investigation to associate the use of polynucleotides and hyaluronic acid with bovine bone in maxillary sinus lift procedures in rabbits has not been performed yet. The aim was to evaluate the influence of this novel association on the processes of bone regeneration in maxillary sinus augmentation.

Methods

In this prospective, randomized, within-animal model, maxillary sinus augmentation was performed bilaterally in 12 rabbits. Deproteinized bovine bone material (DBBM) was used as filler material. A hyaluronic acid-polynucleotide gel was aggregated at the test site. Histological evaluations were performed after 2 and 10 weeks of healing.

Results

After 2 weeks of healing, similar amounts of new bone were observed at both the control (7.7 ± 4.

SUBMITTER: Maniwa N 

PROVIDER: S-EPMC11678527 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature