Microstructural Analysis of the Human Scapula: Mandibular Bone Tissue Engineering Perspectives.

ABSTRACT: Mandibular bone defect reconstruction remains a significant challenge for surgeons worldwide. Among multiple biodegradable biopolymers, allogeneic bone scaffolds derived from human sources have been used as an alternative to autologous bone grafts, providing optimal conditions for cell recruitment, adhesion, and proliferation and demonstrating significant osteogenic properties. This study aims to investigate the bone microstructure of the human scapula as a source for allogeneic bone scaffold fabrication for mandibular tissue engineering purposes. We created color-coded anatomical maps of the scapula and the mandible, reflecting the best anatomical and geometrical match. In this pilot study, we hypothesized a microstructural similarity of these bone structures and evaluated the human scapu

SUBMITTER: Tsiklin IL 

PROVIDER: S-EPMC11678577 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature