Correlation between quantitative and semiquantitative magnetic resonance imaging and histopathology findings in dermatomyositis.

ABSTRACT:

Objectives

The aim of this study was to compare muscle biopsy findings, as well as clinical and analytical features, with those of magnetic resonance imaging (MRI) studies of muscle in patients with dermatomyositis.

Methods

All patients from the Longitudinal Myopathy Cohort of the Hospital Clínic de Barcelona were prospectively included in the study from 2009 to 2016. MRI images of muscle and fascial oedema were compared with muscle pathology results using both quantitative and semi-quantitative scores.

Results

We found a statistically significant association between the inflammatory infiltrate and both muscle (r2=0.54, p=0.001) and fascial oedema (r2=0.54, p<0.001). In addition, muscle oedema was significantly associated with punched-out vacuoles (p=0.04) and muscle

SUBMITTER: Milisenda JC 

PROVIDER: S-EPMC11678784 | biostudies-literature | 2019 Jul-Aug

REPOSITORIES: biostudies-literature