Assessment of Mortality in Autoimmune Myositis With and Without Associated Interstitial Lung Disease.

ABSTRACT:

Purpose

Among patients with autoimmune myositis, associated interstitial lung disease (MA-ILD) is a known contributor of excess morbidity and mortality. Recent data on survival in idiopathic inflammatory myopathies originate primarily in Asia and Europe and vary widely. We sought to examine mortality in a large U.S. myositis cohort focusing in particular on the impact of associated ILD.

Methods

A cross-sectional analysis of participants from the Johns Hopkins Myositis Center with autoimmune myositis (polymyositis [PM], dermatomyositis [DM], or clinically amyopathic dermatomyositis [CADM]) was conducted. The primary outcome assessed was all-cause mortality. Cumulative mortality rates were estimated using the Kaplan-Meier test; the Cox proportional hazards model was used to co

SUBMITTER: Johnson C 

PROVIDER: S-EPMC11678787 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature