Antiplatelet Effects of a Combination of Sappan Wood (<i>Caesalpinia sappan</i> L.) and Red Ginger (<i>Zingiber officinale var. Rubrum</i>) Extracts in a High-Fat Diet-Induced Rat Model.

ABSTRACT: Background: Antithrombotic medications, including antiplatelet agents, are standard treatments for patients with hyperlipidemia who have a high risk of developing cardiovascular disease (CVD). The ongoing exploration of new antiplatelet agents with minimal bleeding effects is crucial, including the investigation of potential compounds derived from natural products. This study intended to evaluate the antiplatelet effects of a combined extract of sappan wood (Caesalpinia sappan L.) and red ginger (Zingiber officinale var. Rubrum) in high-fat diet-(HFD)-induced rats. Methods: Eighteen male Wistar rats were grouped into six groups (n = 3): control, negative, positive, and three groups of various combinations of extracts. All groups, excluding the cont

SUBMITTER: Puteri MU 

PROVIDER: S-EPMC11679274 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature