Integration Analysis of Transcriptome Sequencing and Whole-Genome Resequencing Reveal Wool Quality-Associated Key Genes in Zhexi Angora Rabbits.

ABSTRACT: Wool quality is a crucial economic trait in Angora rabbits, closely linked to hair follicle (HF) growth and development. Therefore, understanding the molecular mechanisms of key genes regulating HF growth and wool fiber formation is essential. In the study, fine- and coarse-wool groups were identified based on HF morphological characteristics of Zhexi Angora rabbits. According to the results, the diameters of fine and coarse fibers, and the percentage of coarse fibers, were significantly lower in the fine-wool group than in the coarse-wool group. Additionally, the HF density was higher in the fine-wool group than in the coarse-wool group, and the diameters of both primary hair follicles and second hair follicles were finer in this fine-wool group. Moreover, RNA sequencing (RNA-seq) and who

SUBMITTER: Zhao B 

PROVIDER: S-EPMC11680169 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature