Influenza A Virus Detection at the Human-Swine Interface in US Midwest Swine Farms.

ABSTRACT: This study evaluated influenza A virus (IAV) detection and genetic diversity over time, specifically at the human-swine interface in breeding and nursery farms. Active surveillance was performed monthly in five swine farms in the Midwest United States targeting the employees, the prewean piglets at sow farms, and the same cohort of piglets in downstream nurseries. In addition, information was collected at enrollment for each employee and farm to assess production management practices, IAV vaccination status, diagnostic procedures, and biosecurity. Farm employee and swine samples were screened by IAV reverse transcription real-time polymerase chain reaction (RT-rtPCR), followed by IAV subtyping RT-rtPCR and whole genome sequencing on PCR-positive samples. This study showed higher positivity

SUBMITTER: Moraes DCA 

PROVIDER: S-EPMC11680338 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature