Mycoplasma synoviae Induces Apoptosis in Chicken Oviduct Cells.

ABSTRACT: Mycoplasma synoviae (MS) is an important pathogen that can cause respiratory diseases in poultry and birds, leading to serious economic losses in the world and impacting the development of the poultry industry. However, the pathogenic mechanisms of MS infection are still unclear, resulting in a lack of effective diagnosis and treatment strategies. This study aimed to uncover the infection effect caused by MS in chicken oviduct cells. MS-infected chicken oviduct cells with different infection times and doses were collected, and DAPI staining was performed to monitor the morphological changes of cell nuclei. Cell viability was detect by CCK-8 assay. The expression of marker genes of cell apoptosis was determined by RT-qPCR and Western blotting assay, respectively. The results showed t

SUBMITTER: Zhang X 

PROVIDER: S-EPMC11680356 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature