No Association Between Eosinophilic Oesophagitis and Oesophageal Cancer in US Adults: A Case-Control Study.

ABSTRACT:

Background

While inflammation is implicated in the development of numerous cancers, whether eosinophilic oesophagitis (EoE) increases the risk of oesophageal cancer (OCa) remains understudied.

Aim

To assess whether adults with EoE were more likely to have subsequent OCa diagnosis.

Methods

This case-control study used data from the MarketScan commercial claims database. Cases were 18-64 years old with an oesophageal cancer diagnosis (≥ two coding instances) who had no previous oesophageal cancer code. Controls were matched 10:1 by age and time in health plan. All cases and controls had at least 2 years of continuous healthcare coverage before the index date. EoE status required ≥ two coding instances. We used conditional logistic regression modelling to assess the asso

SUBMITTER: Albaneze N 

PROVIDER: S-EPMC11680457 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature