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ABSTRACT: Introduction
Complex regional pain syndrome (CRPS) is a clinical disorder that can develop following surgery or trauma. Based on the most prominent underlying pathophysiological mechanisms, CRPS can be classified into different subtypes, namely inflammatory, nociplastic/neuropathic, vasomotor, and motor. Depending on the subtype, personalized treatment can be applied. If conservative treatments are insufficient or ineffective, more invasive treatments may be recommended. This article provides an overview of the most recent insights into CRPS and discusses the most common invasive treatments.Methods
The literature regarding interventional treatments for CRPS has been systematically reviewed and summarized.Results
Bisphosphonates are effective in treating the inflamma
SUBMITTER: van der Spek DPC
PROVIDER: S-EPMC11680468 | biostudies-literature | 2025 Jan
REPOSITORIES: biostudies-literature