Self-gated free-running 5D whole-heart MRI using blind source separation for automated cardiac motion extraction.

ABSTRACT:

Purpose

To compare two blind source separation (BSS) techniques to principal component analysis and the electrocardiogram for the identification of cardiac triggers in self-gated free-running 5D whole-heart MRI. To ascertain the precision and robustness of the techniques, they were compared in three different noise and contrast regimes.

Methods

The repeated superior-inferior (SI) projections of a 3D radial trajectory were used to extract the physiological signals in three cardiac MRI cohorts: (1) 9 healthy volunteers without contrast agent injection at 1.5T, (2) 30 ferumoxytol-injected congenital heart disease patients at 1.5T, and (3) 12 gadobutrol-injected patients with suspected coronary artery disease at 3T. Self-gated cardiac triggers were extracted with the three algor

SUBMITTER: Monton Quesada I 

PROVIDER: S-EPMC11680725 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature