Layer-specific BOLD effects in gradient and spin-echo acquisitions in somatosensory cortex.

ABSTRACT:

Purpose

Previous studies have shown varied BOLD signals with gradient echo (GE) across cortical depth. To interpret these variations, and understand the effects of vascular geometry and size, the magnitudes and layer distributions of GE and spin-echo (SE) BOLD functional MRI signals were compared in the somatosensory cortex of squirrel monkeys during tactile stimulation and in a resting state at high spatial resolution and high field.

Methods

A block-design stimulation was used to identify tactile-evoked activation signals in somatosensory Areas 3b and 1. Layer-specific connectivities were calculated using resting-state data. Signal power spectra were compared by depth and pulse sequence. The measured ratios of transverse relaxation rate changes were compared with Anderson a

SUBMITTER: Yang Z 

PROVIDER: S-EPMC11680728 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature