MR-zero meets FLASH - controlling the transient signal decay in gradient- and RF-spoiled gradient echo sequences.

ABSTRACT:

Purpose

The complex signal decay during the transient FLASH MRI readout can lead to artifacts in magnitude and phase images. We show that target-driven optimization of individual RF flip angles and phases can realize near-ideal signal behavior and mitigate artifacts.

Methods

The differentiable end-to-end optimization framework MR-zero is used to optimize RF trains of the FLASH sequence. We focus herein on minimizing deviations from the ideally spoiled signal by using a mono-exponential Look-Locker target. We first obtain the transient FLASH signal decay substructure, and then minimize the deviation to the Look-Locker decay by optimizing the individual (i) flip angles, (ii) RF phases, and (iii) flip angles and RF phases. Comparison between measurement and simulation is perfor

SUBMITTER: Weinmuller S 

PROVIDER: S-EPMC11680739 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature