Outdoor nitrogen dioxide exposure and longitudinal health status trajectory in the Canadian National Population Health Survey.

ABSTRACT: Few studies have examined the association between air pollution and the trajectory of global health status measures related to the functional impacts of chronic disease. To address this gap, we examined the trajectory of the Health Utilities Index (HUI) over 17 years of follow-up among Canadian National Population Health Survey (NPHS) participants. Annual average nitrogen dioxide (NO₂) exposures from a national land use regression surface were mapped to 15,631 NPHS participants at their place of residence provided at each follow-up. We modelled HUI trajectory as a cubic polynomial function of age in relation to air pollution and selected covariates using random growth curve models to account for longitudinal repeated measures. Adjusting for covariates selected based on a directe

SUBMITTER: Stieb DM 

PROVIDER: S-EPMC11681082 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature