Circulating Tumor DNA Testing in Curatively Resected Colorectal Cancer and Salvage Resection.

ABSTRACT:

Importance

Serial circulating tumor DNA (ctDNA) has emerged as a routine surveillance strategy for patients with resected colorectal cancer, but how serial ctDNA monitoring is associated with potential curative outcomes has not been formally assessed.

Objective

To examine whether there is a benefit of adding serial ctDNA assays to standard-of-care imaging surveillance for potential curative outcomes in patients with resected colorectal cancer.

Design, setting, and participants

In this single-center (City of Hope Comprehensive Cancer Center, Duarte, California), retrospective, case cohort study, patients with stage II to IV colorectal cancer underwent curative resection and were monitored with serial ctDNA assay and National Cancer Center Network (NCCN)-guided imaging

SUBMITTER: Ji J 

PROVIDER: S-EPMC11681374 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature