Genetic Association of Juvenile Idiopathic Arthritis With Adult Rheumatic Disease.

ABSTRACT:

Importance

Patients with juvenile idiopathic arthritis (JIA) may develop adult rheumatic diseases later in life, and prolonged or recurrent disease activity is often associated with substantial disability; therefore, it is important to identify patients with JIA at high risk of developing adult rheumatic diseases and provide specialized attention and preventive care to them.

Objective

To elucidate the full extent of the genetic association of JIA with adult rheumatic diseases, to improve treatment strategies and patient outcomes for patients at high risk of developing long-term rheumatic diseases.

Design, setting, and participants

In this genetic association study of 4 disease genome-wide association study (GWAS) cohorts from 2013 to 2024 (JIA, rheumatoid arthritis [R

SUBMITTER: Fan J 

PROVIDER: S-EPMC11681380 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature