Sex Differences in Protein Biomarkers and Measures of Fat Distribution.

ABSTRACT:

Background

Sex differences in obesity and fat distribution may in part explain differences in cardiovascular risk in men versus women. We sought to examine sex differences in the associations of obesity and adiposity measures with cardiovascular disease-related protein biomarkers.

Methods and results

In a cross-sectional observational cohort study, we examined whether the association of obesity (body mass index [BMI] and waist circumference) and adiposity measures (visceral adipose tissue) with biomarkers demonstrates effect modification by sex using multiplicative interaction terms in multivariable linear regression models. Among 3143 participants (mean age, 50 years; 49% women), sex modified the association of BMI, waist circumference, and visceral adipose tissue with card

SUBMITTER: Ramirez MF 

PROVIDER: S-EPMC11681412 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature