CCL3 as a novel biomarker in the diagnosis of necrotizing enterocolitis.

ABSTRACT:

Objectives

Neonatal necrotizing enterocolitis (NEC) is a common intestinal disease that threatens the lives of newborns and is characterized by ischemic necrosis of the small intestine and colon. As early diagnosis of NEC improves prognosis, the identification of new or complementary biomarkers is of great importance. In this study, we evaluate the diagnostic value of CCL3 in NEC and compare its effectiveness with other commonly used biomarkers, such as procalcitonin (PCT) and C-reactive protein (CRP).

Participants and design

Serum samples were collected from 64 patients with NEC and 38 jaundice neonatal controls. Before initiating therapy, blood samples for the whole blood count, CRP, PCT and CCL3 were obtained from all neonates. Receiver operating characteristic (ROC) curv

SUBMITTER: Zeng L 

PROVIDER: S-EPMC11681690 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature