Fetuin-A levels in diabetic retinopathy: a systematic review and meta-analysis.

ABSTRACT:

Background

Diabetic retinopathy (DR) is one of the main microvascular complications of diabetes and one of the most common causes of vision loss worldwide. Fetuin-A is a glycoprotein correlated with insulin resistance and has been measured in DR patients. Herein, we aimed to investigate these studies through a systematic review and meta-analysis.

Methods

Four online databases, including PubMed, Embase, Scopus, and the Web of Science were searched comprehensively in order to retrieve relevant studies that compared blood fetuin-A levels in patients with DR vs. non-DR, DR vs. non-diabetic controls, non-DR vs. non-diabetic controls, and proliferative vs. non- proliferative DR. Random-effect meta-analysis was performed for the calculation of the standardized mean difference (SMD)

SUBMITTER: Behnoush AH 

PROVIDER: S-EPMC11682028 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature