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Application of Fourier transform infrared spectroscopy to exhaled breath analysis for detecting helicobacter pylori infection.


ABSTRACT: Helicobacter pylori (H. pylori) is one of the most globally prevalent bacteria, closely associated with gastrointestinal diseases such as gastric ulcers and chronic gastritis. Current clinical methods primarily involve Carbon-13 and Carbon-14 urea breath test, both carrying potential safety risks. Fourier-transform infrared (FTIR) spectroscopy can detect human exhaled gases, which may change under disease conditions. This preliminary study aims to explore the application value of FTIR-based breath analysis in detecting H. pylori infection, providing theoretical basis and clinical references for new clinical detection methods. A cross-sectional survey was conducted from August 2021 to May 2022 at Renmin Hospital of Wuhan University. Breath samples were collected before and half an hour afte

SUBMITTER: Qiu M 

PROVIDER: S-EPMC11682097 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature